Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.36 |
| ▸ | ADK | P55263 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26276093 | 1.00 | POLRMT (0.49) | POLRMTFGFR1ADKCYP3A4CYP2D6 | |
| SCHEMBL26276089 | 0.97 | POLRMT (0.49) | POLRMTFGFR1ADKCYP3A4CYP2D6 | |
| SCHEMBL26276152 | 0.91 | POLRMT (0.46) | POLRMT | |
| SCHEMBL26285621 | 0.88 | POLRMT (0.51) | POLRMTFGFR1ADKCYP3A4CYP2D6 | |
| SCHEMBL25077210 | 0.88 | POLRMT (0.51) | POLRMTFGFR1ADKCYP3A4CYP2D6 | |
| SCHEMBL31077590 | 0.88 | POLRMT (0.49) | POLRMT | |
| SCHEMBL26276140 | 0.87 | POLRMT (0.43) | POLRMT | |
| SCHEMBL25077108 | 0.87 | POLRMT (0.43) | POLRMTFGFR1ADK | |
| SCHEMBL26275953 | 0.87 | POLRMT (0.43) | POLRMTFGFR1ADK | |
| SCHEMBL25077182 | 0.86 | POLRMT (0.43) | POLRMTADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023527-A1 | PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-02-23 | — | — | WO | disclosed |