SCHEMBL25077263

CCCCCCCCCCCCCCCCCCC[C@H](COP(=O)(O)OC[C@@]1(C#N)O[C@@H](c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O)Oc1cc(OC)c(C#N)c(OCCCCCCCCCCCCCCCCCCC[C@H](COP(=O)(O)OC[C@@]2(C)O[C@@H](c3ccc4c(N)ncnn34)[C@H](O)[C@@H]2O)Oc2ccc(C#N)c(OC(C)C)c2)c1

nearest known ligand 0.37

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	POLRMT	O00411	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25077090	0.97	POLRMT (0.36)	POLRMT
SCHEMBL25077246	0.93	POLRMT (0.39)	POLRMT
SCHEMBL25077213	0.91	POLRMT (0.41)	POLRMT
SCHEMBL25769868	0.91	POLRMT (0.41)	POLRMT
SCHEMBL25076965	0.91	POLRMT (0.41)	POLRMT
SCHEMBL25762452	0.91	POLRMT (0.41)	POLRMT
SCHEMBL25765236	0.89	POLRMT (0.42)	POLRMT
SCHEMBL25762090	0.89	POLRMT (0.42)	POLRMT
SCHEMBL25076959	0.89	POLRMT (0.40)	POLRMT
SCHEMBL25077012	0.88	POLRMT (0.40)	POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023023527-A1	PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME	GILEAD SCIENCES, INC. (US)	2023-02-23	—	—	WO	disclosed