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SCHEMBL25077308

SCHEMBL25077308

CCCCCCCCCCCCCCCCOC[C@@H](COP(=O)(O)OC1[C@@]2(C)O[C@@H](c3ccc4c(N)ncnn34)[C@H](O)[C@@]12O)OCc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.37
▸ AKT1 P31749 6/20 0.34
▸ AKT2 P31751 5/20 0.34
▸ AKT3 Q9Y243 5/20 0.34
▸ PIK3R1 P27986 4/20 0.34
▸ PIK3CA P42336 4/20 0.34
▸ PLCG2 P16885 1/20 0.34
▸ GAB1 Q13480 1/20 0.34
▸ LPAR1 Q92633 2/20 0.31
▸ LPAR3 Q9UBY5 2/20 0.31
▸ MAPK14 Q16539 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25764493 1.00 POLRMT (0.37) POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25773415 1.00 POLRMT (0.37) POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25077160 0.94 POLRMT (0.38) POLRMT
SCHEMBL25077563 0.90 POLRMT (0.36) POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25773860 0.90 POLRMT (0.34) POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25773864 0.90 POLRMT (0.34) POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL26286033 0.90 POLRMT (0.37) POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25773425 0.89 POLRMT (0.35) POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25770948 0.89 POLRMT (0.35) POLRMTAKT1AKT2AKT3PIK3R1
SCHEMBL25077331 0.88 POLRMT (0.33) POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023023527-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2023-02-23 — — WO disclosed
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