SCHEMBL25077337

SCHEMBL25077337

CCCCCCCCCCCCCCCCCCOCC(COP(=O)(O)OC[C@]1(C)CC[C@H](c2ccc3c(N)ncnn23)O1)OCc1cnc(C#N)cn1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.34
▸ FGFR1 P11362 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25766926 1.00 POLRMT (0.34) POLRMTFGFR1
SCHEMBL25770159 0.93 POLRMT (0.34) POLRMTFGFR1
SCHEMBL25771304 0.92 POLRMT (0.33) POLRMT
SCHEMBL25766689 0.90 POLRMT (0.35) POLRMTFGFR1
SCHEMBL25767737 0.89 POLRMT (0.34) POLRMTFGFR1
SCHEMBL25077262 0.89 POLRMT (0.41) POLRMT
SCHEMBL25764867 0.89 POLRMT (0.41) POLRMT
SCHEMBL25077542 0.88 POLRMT (0.34) POLRMT
SCHEMBL25766845 0.87 POLRMT (0.33) POLRMT
SCHEMBL25077232 0.87 POLRMT (0.34) POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023023527-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2023-02-23 — — WO disclosed
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