Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 4/20 | 0.30 |
| ▸ | AKT2 | P31751 | 3/20 | 0.30 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.30 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.30 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25077242 | 1.00 | POLRMT (0.33) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25773362 | 0.93 | POLRMT (0.33) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25773376 | 0.93 | POLRMT (0.33) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25077525 | 0.93 | POLRMT (0.33) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25077278 | 0.93 | POLRMT (0.33) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25077190 | 0.91 | POLRMT (0.34) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25077356 | 0.89 | POLRMT (0.33) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25077538 | 0.89 | POLRMT (0.33) | POLRMTAKT1AKT2AKT3PIK3R1 | |
| SCHEMBL25077194 | 0.88 | POLRMT (0.34) | POLRMT | |
| SCHEMBL25077609 | 0.88 | POLRMT (0.33) | POLRMTAKT1AKT2AKT3PIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023527-A1 | PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-02-23 | — | — | WO | disclosed |