SCHEMBL250774

SCHEMBL250774

C=CC[Si](CC=C)CC=C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5881391 0.78
SCHEMBL5881344 0.78
SCHEMBL5881428 0.73 TSHR (0.38) TSHRALDH1A1
SCHEMBL5881343 0.73 TSHR (0.38) TSHRALDH1A1
SCHEMBL8586597 0.73 TSHR (0.33) TSHRALDH1A1
SCHEMBL9245799 0.70
SCHEMBL6413586 0.67
SCHEMBL5881387 0.67
SCHEMBL1478783 0.67
SCHEMBL5881380 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2496 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118185269-A Branched triallyl siliceous polycarbonate and preparation method thereof 中国石油天然气股份有限公司 2024-06-14 CN claimed
EP-3807244-B1 SPHINGOSINE/SPHINGOID BASE PRODUCTION CARBOCODE S A (PT) 2024-03-13 EP claimed
CN-112368261-B Sphingosine/sphingosine base production 碳码股份公司 2024-02-20 CN claimed
US-11851446-B2 Probes for imaging Huntingtin protein CHDI FOUNDATION, INC. (US) 2023-12-26 US claimed
EP-3717494-B1 HIGHLY ISOSELECTIVE CATALYST FOR ALKENE HYDROFORMYLATION EASTMAN CHEM CO (US) 2023-11-01 EP claimed
US-20230132715-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-05-04 US claimed
US-11389438-B2 Compounds for targeting mutant huntingtin protein and uses thereof CHDI FOUNDATION, INC. (US) 2022-07-19 US claimed
US-11278482-B2 Process for dyeing keratin materials using at least one blue, purple or green dye and at least one disulfide, thiol or protected thiol fluorescent dye L'OREAL (FR) 2022-03-22 US claimed
EP-3931186-A1 COMPOUNDS FOR TARGETING MUTANT HUNTINGTIN PROTEIN AND USES THEREOF CHDI Foundation, Inc. (US) 2022-01-05 EP claimed
EP-3197277-B1 PROBES FOR IMAGING HUNTINGTIN PROTEIN CHDI FOUNDATION INC (US) 2021-12-22 EP claimed
EP-0096596-A1 Microelectronic device manufacture NEC CORPORATION (JP) 1983-12-21 EP claimed
EP-0082498-A2 Beta-lactam compounds and process for the preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1983-06-29 EP claimed
EP-0059756-A1 7-OXOPROSTACYCLIN DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF. SCHERING AG (DE) 1982-09-15 EP claimed
US-4331559-A Olefin disproportionation PHILLIPS PETROLEUM COMPANY (US) 1982-05-25 US claimed
US-4324729-A PERFUMES, FLAVORS FIRMENICH SA (CH) 1982-04-13 US claimed
WO-1982001002-A1 7-OXOPROSTACYCLIN DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF NICKOLSON R 1982-04-01 WO claimed
US-4056562-A 3,5-Bisoxygenated 2-(ω-halo-3-oxygenated-1-alkenyl)-cyclopentane-1-heptanoic acids and derivatives thereof G. D. SEARLE & CO. (US) 1977-11-01 US claimed
US-4041050-A 3,5-Bisoxygenated 2-(ω-halo-3-oxo-1-alkenyl)-cyclopentane-1-heptanoic acids and derivatives thereof G. D. SEARLE & CO. (US) 1977-08-09 US claimed
US-3997588-A 3,5-Bisoxygenated 2-(ω-halo-3-oxygenated-1-alkenyl)-cyclopentane-1-heptanoic acids and derivatives thereof G. D. SEARLE & CO. (US) 1976-12-14 US claimed
US-3940425-A Process for the production of polyunsaturated compounds BAYER AKTIENGESELLSCHAFT (DT) 1976-02-24 US claimed