Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | TK2 | O00142 | 8/20 | 0.49 |
| ▸ | TK1 | P04183 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11503704 | 1.00 | KIF11 (0.55) | KIF11TK2TK1HRH4LTA4H | |
| SCHEMBL21411547 | 1.00 | KIF11 (0.55) | KIF11TK2TK1HRH4LTA4H | |
| SCHEMBL8142505 | 1.00 | KIF11 (0.55) | KIF11TK2TK1HRH4LTA4H | |
| SCHEMBL4803716 | 1.00 | KIF11 (0.55) | KIF11TK2TK1HRH4LTA4H | |
| SCHEMBL25077100 | 1.00 | KIF11 (0.55) | KIF11TK2TK1HRH4LTA4H | |
| SCHEMBL5820308 | 1.00 | KIF11 (0.55) | KIF11TK2TK1HRH4LTA4H | |
| SCHEMBL5820348 | 1.00 | KIF11 (0.55) | KIF11TK2TK1HRH4LTA4H | |
| SCHEMBL20072694 | 1.00 | KIF11 (0.55) | KIF11TK2TK1HRH4LTA4H | |
| SCHEMBL17243243 | 0.98 | KIF11 (0.57) | KIF11TK2TK1HRH4LTA4H | |
| SCHEMBL4478143 | 0.93 | KIF11 (0.49) | KIF11TK2TK1HRH4LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023527-A1 | PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-02-23 | — | — | WO | disclosed |