SCHEMBL25077437

SCHEMBL25077437

CCCCCCCCCCCCCC[C@@H](COP(=O)(O)OC[C@@]1(C)O[C@@H](c2ccc3c(N)ncnn23)[C@@H]2OC(C)(C)O[C@@H]21)OCc1cc(F)cc(C#N)c1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25777707 1.00 POLRMT (0.34) POLRMT
SCHEMBL25784549 1.00 POLRMT (0.34) POLRMT
SCHEMBL25777385 1.00 POLRMT (0.34) POLRMT
SCHEMBL25777577 1.00 POLRMT (0.34) POLRMT
SCHEMBL25077529 1.00 POLRMT (0.34) POLRMT
SCHEMBL25779501 1.00 POLRMT (0.34) POLRMT
SCHEMBL25077517 1.00 POLRMT (0.34) POLRMT
SCHEMBL25077543 1.00 POLRMT (0.34) POLRMT
SCHEMBL25784583 0.95 POLRMT (0.34) POLRMT
SCHEMBL25782928 0.95 POLRMT (0.34) POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023023527-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2023-02-23 — — WO disclosed
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