SCHEMBL25077556

SCHEMBL25077556

CCCCCCCCCCCCCCCCCC[C@@H](COP(=O)(O)OC[C@@]1(C)O[C@@H](c2ccc3c(N)ncnn23)[C@@H]2OC(C)(C)O[C@@H]21)OCc1cc(Cl)cc(C#N)c1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ POLRMT O00411 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25077535 1.00 POLRMT (0.35) POLRMT
SCHEMBL25077350 1.00 POLRMT (0.35) POLRMT
SCHEMBL25783996 1.00 POLRMT (0.35) POLRMT
SCHEMBL30476185 0.94 POLRMT (0.35) POLRMT
SCHEMBL30476176 0.94 POLRMT (0.35) POLRMT
SCHEMBL30259681 0.94 POLRMT (0.35) POLRMT
SCHEMBL25077481 0.94 POLRMT (0.35) POLRMT
SCHEMBL25077395 0.94 POLRMT (0.35) POLRMT
SCHEMBL30259860 0.94 POLRMT (0.35) POLRMT
SCHEMBL30476177 0.94 POLRMT (0.35) POLRMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023023527-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2023-02-23 — — WO disclosed
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