Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12247914 | 0.86 | HTT (0.48) | ALDH1A1HTTSMN1; SMN2MAPK1USP2 | |
| SCHEMBL14817797 | 0.76 | GSR (0.37) | — | |
| SCHEMBL25077906 | 0.75 | HTT (0.43) | ALDH1A1HTTSMN1; SMN2MAPK1USP2 | |
| SCHEMBL18909066 | 0.73 | HDAC2 (0.32) | ALDH1A1HTTSMN1; SMN2HPGD | |
| SCHEMBL9250163 | 0.73 | HPGD (0.50) | ALDH1A1HTTSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9029735 | 0.69 | POLB (0.37) | ALDH1A1SMN1; SMN2MAPK1KDM4ELMNA | |
| SCHEMBL10510764 | 0.68 | TSHR (0.44) | ALDH1A1HTTSMN1; SMN2HPGDKMT2A | |
| SCHEMBL30046741 | 0.68 | ALDH1A1 (0.73) | ALDH1A1HTTSMN1; SMN2MAPK1USP2 | |
| SCHEMBL7955999 | 0.67 | — | — | |
| SCHEMBL6962688 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023022497-A1 | SOS1 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-02-23 | — | — | WO | disclosed |