Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 20/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24754213 | 0.84 | DDB1 (0.48) | DDB1CRBN | |
| SCHEMBL30257139 | 0.83 | DDB1 (0.51) | DDB1CRBN | |
| SCHEMBL22118175 | 0.80 | DDB1 (0.55) | DDB1CRBN | |
| SCHEMBL29403117 | 0.80 | DDB1 (0.55) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL31174905 | 0.79 | DDB1 (0.54) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL22117971 | 0.79 | DDB1 (0.54) | DDB1CRBN | |
| SCHEMBL31356218 | 0.78 | CRBN (0.56) | DDB1CRBN | |
| SCHEMBL31355986 | 0.78 | CRBN (0.56) | DDB1CRBN | |
| SCHEMBL27363599 | 0.78 | DDB1 (0.58) | DDB1CRBN | |
| SCHEMBL21965762 | 0.77 | DDB1 (0.74) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023531-A1 | ESTROGEN RECEPTOR DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-02-23 | — | — | WO | disclosed |