SCHEMBL29403117

SCHEMBL29403117

O=C1CCC(Nc2cccc(NC(=O)CN3CCNCC3)c2)C(=O)N1

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 13/20 0.55
▸ CRBN Q96SW2 13/20 0.55
▸ POLB P06746 1/20 0.49
▸ JAK3 P52333 1/20 0.46
▸ DRD4 P21917 3/20 0.45
▸ DRD2 P14416 2/20 0.45
▸ DRD3 P35462 2/20 0.45
▸ ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22118175 1.00 DDB1 (0.55) DDB1CRBNPOLBJAK3DRD4
Hydrochloric Acid SCHEMBL31174905 0.99 DDB1 (0.54) DDB1CRBNPOLBJAK3DRD4
Hydrochloric Acid SCHEMBL22117971 0.99 DDB1 (0.54) DDB1CRBNPOLBJAK3DRD4
SCHEMBL31447843 0.94 DDB1 (0.49) DDB1CRBNPOLBJAK3DRD4
SCHEMBL24161552 0.91 DDB1 (0.67) DDB1CRBNPOLBALDH1A1
SCHEMBL22128953 0.89 DDB1 (0.55) DDB1CRBNPOLBDRD4DRD2
SCHEMBL22117961 0.89 DDB1 (0.55) DDB1CRBNPOLBDRD4DRD2
SCHEMBL24161544 0.87 DDB1 (0.52) DDB1CRBNPOLBDRD4DRD2
SCHEMBL24290129 0.86 DDB1 (0.52) DDB1CRBNPOLBDRD4DRD2
SCHEMBL24269267 0.86 DDB1 (0.52) DDB1CRBNPOLBDRD4DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116507333-B Cyclic AMP response element binding protein (CBP) and/or 300KDA adenovirus E1A binding protein (P300) degrading compounds and methods of use 上海睿跃生物科技有限公司 2025-05-09 — — CN disclosed
CN-119219606-A Substituted 3- ((3-aminophenyl) amino) piperidine-2, 6-dione compounds, compositions thereof, and methods of treatment using the same 细胞基因公司 2024-12-31 — — CN disclosed
CN-113453681-B Substituted 3- ((3-aminophenyl) amino) piperidine-2, 6-dione compounds, compositions thereof, and methods of treatment using the same 细胞基因公司 2024-10-11 — — CN disclosed
CN-116507333-A Cyclic AMP response element binding protein (CBP) and/or 300KDA adenovirus E1A binding protein (P300) degrading compounds and methods of use 上海睿跃生物科技有限公司 2023-07-28 — — CN disclosed
WO-2022042707-A1 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN (CBP) AND/OR ADENOVIRAL E1A BINDING PROTEIN OF 300 KDA (P300) DEGRADATION COMPOUNDS AND METHODS OF USE CULLGEN (SHANGHAI) , INC. (CN) 2022-03-03 — — WO disclosed
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