Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 5/20 | 0.42 |
| ▸ | CTSC | P53634 | 5/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.38 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2510831 | 0.88 | SYK (0.46) | SYKPRKCQCDK1CTSCPTK2 | |
| SCHEMBL1938235 | 0.86 | SYK (0.50) | SYKPRKCQCDK1CTSCPTK2 | |
| SCHEMBL1933968 | 0.84 | SYK (0.51) | SYKPRKCQCDK1CTSCPTK2 | |
| SCHEMBL2511679 | 0.82 | SYK (0.46) | SYKPRKCQCDK1CTSCPTK2 | |
| SCHEMBL1935907 | 0.81 | SYK (0.47) | SYKPRKCQCDK1CTSCPTK2 | |
| SCHEMBL1917536 | 0.79 | CDK1 (0.59) | SYKPRKCQCDK1CTSCCNR2 | |
| SCHEMBL1935627 | 0.78 | SYK (0.47) | SYKPRKCQCDK1CTSCPTK2 | |
| SCHEMBL1935474 | 0.78 | SYK (0.45) | SYKPRKCQCDK1CTSCPTK2 | |
| SCHEMBL2508768 | 0.77 | SYK (0.54) | SYKPRKCQCDK1CTSCPTK2 | |
| SCHEMBL1935118 | 0.77 | SYK (0.46) | SYKPRKCQCDK1CTSCPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110245284-A1 | Alkoxy- and Alkylthio-Substituted Anilinopyrimidines | BAYER CROPSCIENCE AG (DE) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245284-A1 | Alkoxy- and Alkylthio-Substituted Anilinopyrimidines | HAX1, AGPS, PYM1 | SYK 1381/4885PRKCQ 3691/4885CDK1 1738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.