Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 11/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | ATR | Q13535 | 7/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PRKDC | P78527 | 2/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.37 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25080355 | 0.84 | MTOR (0.49) | MTORPIK3CDPIK3CAATRCHEK1 | |
| SCHEMBL25080374 | 0.84 | MTOR (0.49) | MTORPIK3CDPIK3CAATRCHEK1 | |
| SCHEMBL25080604 | 0.83 | MTOR (0.42) | MTORPIK3CAATRATMPRKDC | |
| SCHEMBL25080641 | 0.83 | MTOR (0.42) | MTORPIK3CAATRATMPRKDC | |
| SCHEMBL1611443 | 0.82 | MTOR (0.53) | MTORPIK3CDPIK3CAATRCHEK1 | |
| SCHEMBL1611445 | 0.82 | MTOR (0.53) | MTORPIK3CDPIK3CAATRCHEK1 | |
| SCHEMBL2673181 | 0.82 | MTOR (0.53) | MTORPIK3CDPIK3CAATRCHEK1 | |
| SCHEMBL25080372 | 0.80 | MTOR (0.48) | MTORPIK3CDPIK3CAATRCHEK1 | |
| SCHEMBL25080663 | 0.80 | MTOR (0.48) | MTORPIK3CDPIK3CAATRCHEK1 | |
| SCHEMBL25080352 | 0.80 | MTOR (0.50) | MTORPIK3CDPIK3CAATRCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020604-A1 | FIVE-MEMBERED NITROGEN-CONTAINING HETEROCYCLIC AND HETEROARYL DERIVATIVE AND USE THEREOF | 南京大美生物制药有限公司 | 2023-02-23 | — | — | WO | disclosed |