Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 9/20 | 0.42 |
| ▸ | ATR | Q13535 | 12/20 | 0.42 |
| ▸ | ATRIP | Q8WXE1 | 9/20 | 0.42 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25080641 | 1.00 | MTOR (0.42) | MTORATRATRIPNUAK1LCK | |
| SCHEMBL25080791 | 0.83 | MTOR (0.44) | MTORATRATRIPLCK | |
| SCHEMBL25080496 | 0.83 | MTOR (0.44) | MTORATRATRIPLCK | |
| SCHEMBL25080455 | 0.83 | MTOR (0.48) | MTORATRATRIPPIK3CAPRKDC | |
| SCHEMBL25080224 | 0.82 | MTOR (0.48) | MTORATRATRIPNUAK1LCK | |
| SCHEMBL25080573 | 0.81 | MTOR (0.50) | MTORATRATRIPNUAK1LCK | |
| SCHEMBL25080609 | 0.80 | ATR (0.45) | MTORATRATRIPLCK | |
| SCHEMBL25080640 | 0.79 | MTOR (0.44) | MTORATRATRIPNUAK1LCK | |
| SCHEMBL24811148 | 0.78 | PDE2A (0.48) | MTORATRATRIP | |
| SCHEMBL25080295 | 0.78 | MTOR (0.45) | MTORATRATRIPNUAK1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020604-A1 | FIVE-MEMBERED NITROGEN-CONTAINING HETEROCYCLIC AND HETEROARYL DERIVATIVE AND USE THEREOF | 南京大美生物制药有限公司 | 2023-02-23 | — | — | WO | disclosed |