Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 16/20 | 0.56 |
| ▸ | PDCD1 | Q15116 | 7/20 | 0.55 |
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25790888 | 0.87 | ATR (0.63) | ATRPDCD1CD274CHEK1MTOR | |
| SCHEMBL25790962 | 0.87 | ATR (0.63) | ATRPDCD1CD274CHEK1MTOR | |
| SCHEMBL25791058 | 0.84 | ATR (0.57) | ATRPDCD1CD274CHEK1MTOR | |
| SCHEMBL25080596 | 0.83 | ATR (0.63) | ATRPDCD1CD274CHEK1MTOR | |
| SCHEMBL25791090 | 0.83 | ATR (0.57) | ATRPDCD1CD274CHEK1MTOR | |
| SCHEMBL25244279 | 0.83 | ATR (0.74) | ATRPDCD1CD274CHEK1MTOR | |
| SCHEMBL25789858 | 0.83 | ATR (0.74) | ATRPDCD1CD274CHEK1MTOR | |
| SCHEMBL25790221 | 0.83 | ATR (0.55) | ATRPDCD1CD274CHEK1MTOR | |
| SCHEMBL25287637 | 0.81 | ATR (0.62) | ATRPDCD1CD274CHEK1MTOR | |
| SCHEMBL25790196 | 0.81 | ATR (0.62) | ATRPDCD1CD274CHEK1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020604-A1 | FIVE-MEMBERED NITROGEN-CONTAINING HETEROCYCLIC AND HETEROARYL DERIVATIVE AND USE THEREOF | 南京大美生物制药有限公司 | 2023-02-23 | — | — | WO | disclosed |