Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12614403 | 0.83 | CHRM2 (0.43) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL7319174 | 0.80 | CHRM2 (0.41) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL23435952 | 0.80 | CHRM2 (0.41) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL23315373 | 0.80 | CHRM2 (0.41) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL12413666 | 0.79 | CHRM2 (0.40) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL12506844 | 0.77 | CHRM2 (0.47) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL9698309 | 0.75 | CHRM2 (0.37) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL13658288 | 0.75 | CHRM3 (0.41) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL9697942 | 0.75 | CHRM1 (0.45) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL21063808 | 0.74 | CHRNA7 (0.41) | CHRM2CHRM1CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023021149-A1 | PRODRUGS FOR USE IN THE TREATMENT OF TISSUE DAMAGE | UCL BUSINESS LTD (GB) | 2023-02-23 | — | — | WO | disclosed |