Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4282682 | 0.91 | CHRM3 (0.38) | CHRM3CHRM2CYP2D6CHRM1MEN1 | |
| SCHEMBL14619433 | 0.84 | CHRM3 (0.34) | CHRM3DRD2 | |
| SCHEMBL12614403 | 0.78 | CHRM2 (0.43) | CHRM2CYP2D6CHRM1MEN1KMT2A | |
| SCHEMBL7319174 | 0.75 | CHRM2 (0.41) | CHRM2CYP2D6CHRM1MEN1KMT2A | |
| SCHEMBL23315373 | 0.75 | CHRM2 (0.41) | CHRM2CYP2D6CHRM1MEN1KMT2A | |
| SCHEMBL25082064 | 0.75 | CHRM2 (0.41) | CHRM3CHRM2CYP2D6CHRM1MEN1 | |
| SCHEMBL23435952 | 0.75 | CHRM2 (0.41) | CHRM2CYP2D6CHRM1MEN1KMT2A | |
| SCHEMBL12506844 | 0.72 | CHRM2 (0.47) | CHRM3CHRM2CYP2D6CHRM1MEN1 | |
| SCHEMBL25607288 | 0.72 | CHRM2 (0.47) | CHRM3CHRM2CYP2D6CHRM1MEN1 | |
| SCHEMBL15318794 | 0.72 | CHRM2 (0.57) | CHRM3CHRM2CYP2D6CHRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414762-B2 | Amides of acetic and propionic acids | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-09-17 | — | — | US | disclosed |
| US-9914729-B2 | Amides of acetic and propionic acids | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-03-13 | — | — | US | disclosed |
| US-9914729-B2 | Amides of acetic and propionic acids | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-03-13 | — | — | US | disclosed |
| US-20170183339-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | BAYER HEALTHCARE AG (DE) | 2017-06-29 | — | — | US | disclosed |
| US-20170183339-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | BAYER HEALTHCARE AG (DE) | 2017-06-29 | — | — | US | disclosed |
| US-9433614-B2 | Amides of acetic and propionic acids | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-06 | — | — | US | disclosed |
| US-9433614-B2 | Amides of acetic and propionic acids | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-06 | — | — | US | disclosed |
| US-20160022651-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2016-01-28 | — | — | US | disclosed |
| US-20160022651-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2016-01-28 | — | — | US | disclosed |
| US-9000008-B2 | Amides of acetic and propionic acids | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-07 | — | — | US | disclosed |
| US-9000008-B2 | Amides of acetic and propionic acids | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-07 | — | — | US | disclosed |
| US-8518967-B2 | Amides of acetic and propionic acids | BAYER HEALTHCARE AG (DE) | 2013-08-27 | — | — | US | disclosed |
| US-8518967-B2 | Amides of acetic and propionic acids | BAYER HEALTHCARE AG (DE) | 2013-08-27 | — | — | US | disclosed |
| US-20090258898-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | BAYER HEALTHCARE AG (DE) | 2009-10-15 | — | — | US | disclosed |
| US-20090258898-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | BAYER HEALTHCARE AG (DE) | 2009-10-15 | — | — | US | disclosed |
| US-7553851-B2 | Amides of acetic and propionic acids | BAYER HEALTHCARE AG (DE) | 2009-06-30 | — | — | US | disclosed |
| US-7553851-B2 | Amides of acetic and propionic acids | BAYER HEALTHCARE AG (DE) | 2009-06-30 | — | — | US | disclosed |
| US-20070037844-A1 | 2-(1-Azabicyclo[2.2.2]oct-3-yl)-N-(7-bromo-1-benzothien-2-yl)acetamide hydrochloride; nicotinic receptor agonists; cognition activators; learning enhancement; nootropic agents; demetia; cholinergic agents; Alzheimer's disease; brain traumas; stroke; attention deficit disorder; schizophrenia | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | US | disclosed |
| US-20070037844-A1 | 2-(1-Azabicyclo[2.2.2]oct-3-yl)-N-(7-bromo-1-benzothien-2-yl)acetamide hydrochloride; nicotinic receptor agonists; cognition activators; learning enhancement; nootropic agents; demetia; cholinergic agents; Alzheimer's disease; brain traumas; stroke; attention deficit disorder; schizophrenia | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022651-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | HCAR2, HCAR3, NAAA | CHRM3 74/4885CHRM2 37/4885CYP2D6 3758/4885 |
| US-20170183339-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | HCAR2, HCAR3, NAAA | CHRM3 74/4885CHRM2 37/4885CYP2D6 3758/4885 |
| US-20090258898-A1 | AMIDES OF ACETIC AND PROPIONIC ACIDS | HCAR2, HCAR3, NAAA | CHRM3 74/4885CHRM2 37/4885CYP2D6 3758/4885 |
| US-20070037844-A1 | 2-(1-Azabicyclo[2.2.2]oct-3-yl)-N-(7-bromo-1-benzothien-2-yl)acetamide hydrochloride; nicotinic receptor agonists; cognition activators; learning enhancement; nootropic agents; demetia; cholinergic agents; Alzheimer's disease; brain traumas; stroke; attention deficit disorder; schizophrenia | CHRNA2, CHRNA6, CHRNA5 | CHRM3 30/4885CHRM2 15/4885CYP2D6 2605/4885 |
| US-10414762-B2 | Amides of acetic and propionic acids | HCAR2, HCAR3, NAAA | CHRM3 74/4885CHRM2 37/4885CYP2D6 3758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.