Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 3/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25082131 | 0.88 | TLR9 (0.47) | MAP3K7AOC3GRM2LRRK2ACVR1 | |
| SCHEMBL25082097 | 0.87 | MAPK1 (0.46) | SYKMAP3K7WNT3AACVR1FGFR2 | |
| SCHEMBL25082179 | 0.86 | TDO2 (0.54) | TDO2AOC3KCNH2 | |
| SCHEMBL25082092 | 0.81 | TDO2 (0.43) | TDO2AOC3KCNH2 | |
| SCHEMBL30249544 | 0.80 | TDO2 (0.41) | TDO2AOC3KCNH2ACVR1 | |
| SCHEMBL25082164 | 0.80 | TDO2 (0.41) | TDO2AOC3KCNH2ACVR1 | |
| SCHEMBL25082145 | 0.79 | TDO2 (0.41) | TDO2AOC3 | |
| SCHEMBL25082139 | 0.79 | TDO2 (0.41) | TDO2AOC3KCNH2 | |
| SCHEMBL25082163 | 0.79 | TDO2 (0.36) | SYKTDO2AOC3ACVR1 | |
| SCHEMBL25082415 | 0.78 | TDO2 (0.43) | WNT3ATDO2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020512-A1 | SUBSTITUTED PYRIDINE ANALOGUE, PREPARATION METHOD THEREFOR, AND USE THEREOF AS AHR MODULATOR | 成都奥睿药业有限公司 | 2023-02-23 | — | — | WO | disclosed |