Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 3/20 | 0.40 |
| ▸ | NQO2 | P16083 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24338715 | 0.82 | MAOA (0.44) | KDM4EALDH1A1MAPTNSD2ADCY10 | |
| SCHEMBL31600539 | 0.82 | KMT2A (0.40) | KDM4EALDH1A1MAPTNSD2ATM | |
| SCHEMBL31714324 | 0.81 | JAK2 (0.38) | KDM4EALDH1A1MAPTNSD2ADCY10 | |
| SCHEMBL22835071 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL25195176 | 0.79 | FGFR1 (0.45) | KDM4EALDH1A1MAPTNSD2GAA | |
| SCHEMBL25083060 | 0.79 | MAPT (0.49) | KDM4EALDH1A1MAPT | |
| SCHEMBL17785196 | 0.79 | IRAK4 (0.47) | KDM4EALDH1A1MAPTGAAHSD17B10 | |
| SCHEMBL20606472 | 0.78 | IRAK4 (0.58) | KDM4EALDH1A1JAK2 | |
| SCHEMBL26386846 | 0.77 | IRAK4 (0.46) | KDM4EALDH1A1CFTR | |
| SCHEMBL22421382 | 0.76 | IRAK4 (0.51) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813006-A | Methods for controlling diamide-resistant pests and compounds thereof | 先正达农作物保护股份公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2023021020-A1 | METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR | SYNGENTA CROP PROTECTION AG (CH) | 2023-02-23 | — | — | WO | disclosed |