Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 10/20 | 0.49 |
| ▸ | CDC25B | P30305 | 8/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.46 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124670 | 0.86 | PDPK1 (0.47) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL6303776 | 0.86 | TACR2 (0.48) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL3898367 | 0.84 | NT5E (0.54) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL3898371 | 0.84 | NT5E (0.54) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL15968116 | 0.84 | NT5E (0.54) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL17766609 | 0.84 | NT5E (0.54) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL29410628 | 0.84 | PTPN1 (0.56) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL10912453 | 0.84 | SLC6A2 (0.51) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL6252622 | 0.84 | SLC6A2 (0.51) | PTPN1CDC25BPTPN2PTPN11PTPN6 | |
| SCHEMBL1039870 | 0.84 | SLC6A2 (0.51) | PTPN1CDC25BPTPN2PTPN11PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028338-A2 | MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2023-03-02 | — | — | WO | disclosed |