SCHEMBL25084266

SCHEMBL25084266

O=C(N[C@@H]1[C@H]2OC[C@](CCP(=O)(O)O)(O2)[C@@H](O)[C@@H]1O)C(F)(F)F

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ASGR1 P07306 15/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25084098 0.84 ASGR1 (0.70) ASGR1
SCHEMBL17256336 0.84 ASGR1 (1.00) ASGR1
SCHEMBL25083858 0.77 ASGR1 (0.41) ASGR1
SCHEMBL25084264 0.75 ASGR1 (0.41) ASGR1
SCHEMBL26879913 0.75 ASGR1 (0.65) ASGR1
SCHEMBL24256177 0.75 ASGR1 (0.65) ASGR1
SCHEMBL25867163 0.74 ASGR1 (0.64) ASGR1
SCHEMBL26698324 0.74 ASGR1 (0.64) ASGR1
SCHEMBL26888865 0.74 ASGR1 (0.64) ASGR1
SCHEMBL26879886 0.73 ASGR1 (0.60) ASGR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023028338-A2 MANNOSE 6-PHOSPHATE OR ASGPR RECEPTOR BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2023-03-02 — — WO disclosed
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