Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | RBP1 | P09455 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 3/20 | 0.32 |
| ▸ | CCND1 | P24385 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23103155 | 0.87 | PANK3 (0.34) | PTPN11PANK3HRH3CHRNB2CHRNA4 | |
| SCHEMBL23102755 | 0.87 | KCNH2 (0.39) | KCNH2CYP2C8CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL23102752 | 0.87 | KCNH2 (0.37) | KCNH2CYP2C8CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL23103195 | 0.85 | MEN1 (0.39) | KCNH2CYP2C8CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL21267344 | 0.85 | CDK4 (0.38) | PTPN11PANK3SYKCHRNB2CHRNA4 | |
| SCHEMBL23108678 | 0.84 | EGFR (0.41) | KCNH2CYP2C8CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL23103196 | 0.83 | SMN1; SMN2 (0.44) | KCNH2CYP2C8CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL23108914 | 0.82 | POLB (0.39) | SYKPCSK9CDK4CCND1CDK6 | |
| SCHEMBL21267346 | 0.82 | PIK3CA (0.42) | KCNH2PTPN11SYKCHRNB2CHRNA4 | |
| SCHEMBL17660307 | 0.82 | TRPV3 (0.36) | SYKCHRNB2CHRNA4CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230062022-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC (US) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230062022-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | CDK4, CDK6, CDK8 | KCNH2 4126/4885CYP2C8 1109/4885CYP2C9 2514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.