⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2508717 | 1.00 | — | — | |
| SCHEMBL2508721 | 1.00 | — | — | |
| SCHEMBL2508723 | 1.00 | — | — | |
| SCHEMBL2511664 | 0.91 | CDC25A (0.34) | — | |
| SCHEMBL2511659 | 0.91 | CDC25A (0.34) | — | |
| SCHEMBL2511661 | 0.91 | CDC25A (0.34) | — | |
| SCHEMBL2511662 | 0.91 | CDC25A (0.34) | — | |
| SCHEMBL12197596 | 0.91 | CDC25A (0.34) | — | |
| SCHEMBL20040523 | 0.81 | TDP1 (0.35) | — | |
| SCHEMBL2507322 | 0.81 | L3MBTL1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534140-B1 | EFFICIENT METHODS FOR Z- OR CIS-SELECTIVE CROSS-METATHESIS | TRUSTEES BOSTON COLLEGE (US) | 2018-04-11 | — | — | EP | disclosed |
| US-8598400-B2 | Efficient methods for Z- or cis-selective cross-metathesis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-12-03 | — | — | US | disclosed |
| US-8552242-B2 | — | — | 2013-10-08 | — | — | US | disclosed |
| US-20110245477-A1 | EFFICIENT METHODS FOR Z- OR CIS-SELECTIVE CROSS-METATHESIS | TRUSTEES OF BOSTON COLLEGE (US) | 2011-10-06 | — | — | US | disclosed |