SCHEMBL2508958

SCHEMBL2508958

CCCc1c(C(C)C)cc(C)c(OC(=O)c2ccccc2)c1OC(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARG P37231 4/20 0.41
PPARA Q07869 4/20 0.41
KMT2A Q03164 4/20 0.40
LMNA P02545 3/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 3/20 0.38
MEN1 O00255 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38
HSP90AB1 P08238 1/20 0.37
GLRA1 P23415 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2501039 0.95 LMNA (0.39) PPARGPPARAKMT2ALMNAALDH1A1
SCHEMBL2508117 0.91 KMT2A (0.41) PPARAKMT2ALMNAALDH1A1MAPT
SCHEMBL2480119 0.89 LMNA (0.40) PPARGPPARAKMT2ALMNAALDH1A1
SCHEMBL2885469 0.89 PPARG (0.44) PPARGPPARAKMT2ALMNAMAPT
SCHEMBL2506721 0.87 KMT2A (0.38) KMT2ALMNAALDH1A1MAPTMEN1
SCHEMBL2509760 0.85 PPARG (0.41) PPARGPPARAKMT2ALMNAALDH1A1
SCHEMBL2485390 0.85 LMNA (0.45) PPARGPPARAKMT2ALMNAALDH1A1
SCHEMBL2511648 0.84 LMNA (0.39) PPARGPPARAKMT2ALMNAALDH1A1
SCHEMBL2504096 0.83 PPARG (0.46) PPARGPPARAKMT2ALMNAALDH1A1
SCHEMBL2479731 0.83 MAPT (0.43) PPARGPPARAKMT2ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2376423-A1 PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS Dow Global Technologies LLC (US) 2011-10-19 EP disclosed
WO-2010078519-A1 PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-08 WO disclosed