Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25090458 | 0.85 | ADORA2A (0.75) | ADORA2BADORA2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL25090447 | 0.84 | ADORA2B (0.67) | ADORA2BADORA2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL25089914 | 0.83 | ADORA2B (0.76) | ADORA2BADORA2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL9568729 | 0.80 | ADORA2A (0.63) | ADORA2BADORA2AKDM4ECYP1A2ADORA1 | |
| SCHEMBL10609344 | 0.80 | KDM4E (0.77) | ADORA2BADORA2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL25090648 | 0.78 | ADORA2B (0.68) | ADORA2BADORA2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL515769 | 0.78 | ADORA2B (1.00) | ADORA2BADORA2AKDM4ECYP1A2ADORA1 | |
| SCHEMBL25090477 | 0.78 | KDM4E (0.61) | ADORA2BADORA2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL10723936 | 0.78 | ADORA2B (1.00) | ADORA2BADORA2AKDM4ECYP1A2ADORA1 | |
| SCHEMBL25089912 | 0.77 | ADORA2A (0.74) | ADORA2BADORA2AKDM4ECYP1A2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023867-A1 | COMPOUNDS FOR REDUCING CHOLESTEROL AND TREATING LIVER AND KIDNEY DISEASE | MCMASTER UNIVERSITY (CA) | 2023-03-02 | — | — | WO | disclosed |