Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15743793 | 0.88 | SMN1; SMN2 (0.60) | CYP3A4SMN1; SMN2PSMB1PSMB5PSMB2 | |
| SCHEMBL22057964 | 0.86 | CYP3A4 (0.58) | CYP3A4SMN1; SMN2PSMB1PSMB5PSMB2 | |
| SCHEMBL82830 | 0.85 | ALDH1A1 (0.60) | CYP3A4SMN1; SMN2L3MBTL1NR1I2ALDH1A1 | |
| P-Xylene SCHEMBL6845696 | 0.85 | ALDH1A1 (0.60) | CYP3A4SMN1; SMN2L3MBTL1NR1I2ALDH1A1 | |
| SCHEMBL19687568 | 0.82 | SMN1; SMN2 (0.66) | CYP3A4SMN1; SMN2PSMB1PSMB5PSMB2 | |
| SCHEMBL18644007 | 0.81 | ALDH1A1 (0.56) | CYP3A4SMN1; SMN2L3MBTL1NR1I2ALDH1A1 | |
| Alcohol SCHEMBL10789814 | 0.81 | NR1I2 (0.60) | CYP3A4SMN1; SMN2L3MBTL1NR1I2ALDH1A1 | |
| SCHEMBL24678322 | 0.81 | CYP3A4 (0.49) | CYP3A4SMN1; SMN2PSMB1PSMB5PSMB2 | |
| SCHEMBL10023257 | 0.80 | CYP3A4 (0.51) | CYP3A4SMN1; SMN2PSMB1PSMB5PSMB2 | |
| SCHEMBL9818198 | 0.80 | SMN1; SMN2 (0.68) | CYP3A4SMN1; SMN2PSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653615-B1 | CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING SAME, AND OPTICAL ARTICLE COMPRISING CURED PRODUCT FORMED OF CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2023-03-01 | — | — | EP | disclosed |