Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | GAA | P10253 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | THRB | P10828 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.71 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.71 |
| ▸ | GFER | P55789 | 3/20 | 0.66 |
| ▸ | RAD52 | P43351 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15358737 | 0.92 | MAPT (0.81) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL6272228 | 0.87 | ALDH1A1 (0.86) | MAPTALDH1A1GAAMEN1THRB | |
| Hydrochloric Acid SCHEMBL7051020 | 0.85 | ALDH1A1 (0.89) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL187881 | 0.85 | ALDH1A1 (0.71) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL29477783 | 0.85 | ALDH1A1 (0.71) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL7031588 | 0.85 | ALDH1A1 (0.89) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL6156455 | 0.85 | ALDH1A1 (0.96) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL18951242 | 0.84 | MAPT (0.69) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL241271 | 0.83 | ALDH1A1 (0.93) | MAPTALDH1A1GAAMEN1THRB | |
| SCHEMBL13345770 | 0.81 | MAPT (0.71) | MAPTALDH1A1GAAMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230065740-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230065740-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | CDK2, CDK1, CCNK | MAPT 3636/4885ALDH1A1 4227/4885GAA 3009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.