Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | USP28 | Q96RU2 | 6/20 | 0.36 |
| ▸ | USP25 | Q9UHP3 | 5/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31082627 | 0.97 | FGFR3 (0.39) | FGFR3PTK6AURKBMAPKAPK2CSF1R | |
| SCHEMBL25096793 | 0.93 | USP28 (0.41) | FGFR3PTK6AURKBMAPKAPK2ALDH1A1 | |
| SCHEMBL30217695 | 0.92 | USP28 (0.41) | FGFR3PTK6AURKBMAPKAPK2ALDH1A1 | |
| SCHEMBL25096319 | 0.92 | USP28 (0.41) | FGFR3PTK6AURKBMAPKAPK2ALDH1A1 | |
| SCHEMBL25096717 | 0.92 | PRNP (0.42) | FGFR3ALDH1A1 | |
| SCHEMBL30217746 | 0.91 | MAPKAPK2 (0.38) | PTK6AURKBMAPKAPK2ALDH1A1USP28 | |
| SCHEMBL29256953 | 0.91 | MAPKAPK2 (0.38) | PTK6AURKBMAPKAPK2ALDH1A1USP28 | |
| SCHEMBL25096532 | 0.91 | MAPKAPK2 (0.35) | PTK6AURKBMAPKAPK2ALDH1A1USP28 | |
| SCHEMBL25095816 | 0.91 | CSF1R (0.40) | FGFR3PTK6AURKBCSF1RALDH1A1 | |
| SCHEMBL30217728 | 0.91 | CSF1R (0.40) | FGFR3PTK6AURKBCSF1RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034811-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| EP-4110464-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2023-01-04 | — | — | EP | disclosed |