Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.40 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30217692 | 1.00 | BACE1 (0.43) | BACE1SLC2A1MAPTMEN1KMT2A | |
| SCHEMBL30217575 | 0.89 | CKS1B (0.44) | BACE1SLC2A1MAPTMEN1KMT2A | |
| SCHEMBL25096858 | 0.89 | CKS1B (0.44) | BACE1SLC2A1MAPTMEN1KMT2A | |
| SCHEMBL25096826 | 0.88 | BACE1 (0.42) | BACE1SLC2A1MAPTSMN1; SMN2SMPD3 | |
| SCHEMBL30217688 | 0.88 | BACE1 (0.42) | BACE1SLC2A1MAPTSMN1; SMN2SMPD3 | |
| SCHEMBL30312627 | 0.84 | SMARCA2 (0.42) | BACE1SLC2A1MAPTMEN1KMT2A | |
| SCHEMBL4185271 | 0.84 | MEN1 (0.44) | BACE1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2878919 | 0.84 | MAP4K4 (0.43) | BACE1SLC2A1MAPTMEN1KMT2A | |
| SCHEMBL29256966 | 0.83 | BACE1 (0.41) | BACE1SLC2A1MAPTMEN1KMT2A | |
| SCHEMBL30217876 | 0.83 | BACE1 (0.41) | BACE1SLC2A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234724-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2024-06-21 | — | — | CN | disclosed |
| WO-2023034811-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |