Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.44 |
| ▸ | SKP1 | P63208 | 2/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30217575 | 1.00 | CKS1B (0.44) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL25096832 | 0.89 | BACE1 (0.43) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL30217692 | 0.89 | BACE1 (0.43) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL30217766 | 0.87 | CKS1B (0.43) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL25096668 | 0.87 | CKS1B (0.43) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL4185271 | 0.85 | MEN1 (0.44) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL2878919 | 0.85 | MAP4K4 (0.43) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL30161994 | 0.83 | SMARCA2 (0.44) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL25095904 | 0.82 | POLB (0.42) | CKS1BSKP1SKP2MAP4K4GPR119 | |
| SCHEMBL30217642 | 0.82 | POLB (0.42) | CKS1BSKP1SKP2MAP4K4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234724-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2024-06-21 | — | — | CN | disclosed |
| WO-2023034811-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |