Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30217579 | 1.00 | GPR119 (0.42) | GPR119RETKITBACE1SMARCA2 | |
| SCHEMBL25096370 | 0.92 | BACE1 (0.40) | GPR119RETKITBACE1SMARCA2 | |
| SCHEMBL30217836 | 0.92 | BACE1 (0.40) | GPR119RETKITBACE1SMARCA2 | |
| SCHEMBL30217822 | 0.89 | BACE1 (0.42) | GPR119RETKITBACE1SMARCA2 | |
| SCHEMBL25096369 | 0.89 | BACE1 (0.42) | GPR119RETKITBACE1SMARCA2 | |
| SCHEMBL25096266 | 0.88 | GPR119 (0.43) | GPR119KITBACE1SMARCA2SMARCA4 | |
| SCHEMBL30217819 | 0.88 | GPR119 (0.43) | GPR119KITBACE1SMARCA2SMARCA4 | |
| SCHEMBL25095896 | 0.86 | CKS1B (0.41) | GPR119RETKITBACE1POLB | |
| SCHEMBL30217840 | 0.86 | CKS1B (0.41) | GPR119RETKITBACE1POLB | |
| SCHEMBL30161994 | 0.82 | SMARCA2 (0.44) | GPR119KITBACE1SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234724-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2024-06-21 | — | — | CN | disclosed |
| WO-2023034811-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |