Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22591153 | 0.88 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL21541238 | 0.77 | HTT (0.36) | SMN1; SMN2HTTMAPTLMNAMAPK1 | |
| SCHEMBL17718026 | 0.72 | ALDH1A1 (0.40) | SMN1; SMN2HTTMAPTL3MBTL1LMNA | |
| SCHEMBL27857856 | 0.71 | MAPT (0.34) | MAPTMEN1KMT2A | |
| SCHEMBL16120608 | 0.65 | MEN1 (0.33) | SMN1; SMN2HTTMAPTL3MBTL1LMNA | |
| SCHEMBL28409735 | 0.64 | POLB (0.32) | — | |
| SCHEMBL20528659 | 0.63 | AHR (0.37) | LMNAMEN1KMT2AALDH1A1 | |
| Formamide SCHEMBL28462456 | 0.63 | POLB (0.38) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL27755208 | 0.62 | POLB (0.42) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL19553576 | 0.62 | PRKCH (0.32) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3763717-B1 | PYRIDO[4,3-D][1,3]OXAZIN-2-ONE COMPOUNDS AS MUTANT IDH1 AND IDH2 INHIBITORS | LILLY CO ELI (US) | 2023-03-08 | — | — | EP | disclosed |