Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | PTAFR | P25105 | 5/20 | 0.35 |
| ▸ | FLT1 | P17948 | 2/20 | 0.33 |
| ▸ | FLT4 | P35916 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23956282 | 0.91 | KDR (0.40) | KDRTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL25100886 | 0.88 | MC4R (0.38) | BRS3PTAFRCYP11B1CYP11B2CYP3A4 | |
| SCHEMBL21290398 | 0.87 | BRS3 (0.34) | BRS3KDRFLT1FLT4CYP3A4 | |
| SCHEMBL21289929 | 0.83 | BRS3 (0.39) | BRS3CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL21289928 | 0.81 | BRS3 (0.38) | BRS3PTAFRCYP11B1CYP11B2CYP3A4 | |
| SCHEMBL25100522 | 0.79 | KDR (0.32) | KDR | |
| SCHEMBL23956276 | 0.78 | KDR (0.41) | KDRFLT1FLT4CYP3A4CYP2C9 | |
| SCHEMBL23956220 | 0.77 | MC4R (0.39) | CYP3A4CYP2C9CYP2C19HIF1ANPC1 | |
| SCHEMBL23956227 | 0.76 | KDR (0.37) | KDRFLT1FLT4CYP3A4CYP2C9 | |
| SCHEMBL23956239 | 0.76 | NR3C2 (0.34) | KDRFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752512-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |