Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 5/20 | 0.38 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.34 |
| ▸ | PTAFR | P25105 | 2/20 | 0.33 |
| ▸ | GAK | O14976 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21289929 | 0.89 | BRS3 (0.39) | BRS3SYK | |
| SCHEMBL23956201 | 0.89 | NPC1 (0.40) | FYNCYP3A4KDM1AMAPTNPC1 | |
| SCHEMBL25100917 | 0.86 | CYP11B1 (0.36) | BRS3FYNCYP11B1CYP11B2CYP3A4 | |
| SCHEMBL21290192 | 0.85 | BRS3 (0.38) | BRS3CYP11B1CYP11B2CYP3A4KDM1A | |
| SCHEMBL25100892 | 0.84 | PTGS2 (0.35) | BRS3CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL25100598 | 0.84 | CYP11B1 (0.42) | BRS3CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL25100886 | 0.83 | MC4R (0.38) | BRS3FYNCYP11B1CYP11B2CYP3A4 | |
| SCHEMBL25100560 | 0.82 | HCRTR1 (0.36) | BRS3MAPTL3MBTL1SYK | |
| SCHEMBL25100532 | 0.81 | CYP11B1 (0.42) | BRS3CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL25100925 | 0.81 | CYP11B1 (0.42) | BRS3CYP11B1CYP11B2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752512-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| WO-2019158453-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-08-22 | — | — | WO | disclosed |