Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337919 | 0.89 | ESR1 (0.50) | ESR1ESR2FOLH1TSHRMIF | |
| SCHEMBL22854043 | 0.86 | LOXL2 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL26305593 | 0.86 | FOLH1 (0.49) | ESR1ESR2FOLH1TSHRMIF | |
| SCHEMBL25100758 | 0.86 | TSHR (0.51) | TSHRCA12CA2CA7CA9 | |
| SCHEMBL6803690 | 0.86 | TSHR (0.51) | TSHRCA12CA2CA7CA9 | |
| SCHEMBL5614085 | 0.85 | ESR1 (0.61) | ESR1ESR2FOLH1TSHRMIF | |
| SCHEMBL24445702 | 0.85 | ESR1 (0.61) | ESR1ESR2FOLH1TSHRMIF | |
| SCHEMBL5614087 | 0.85 | ESR1 (0.61) | ESR1ESR2FOLH1TSHRMIF | |
| SCHEMBL3048692 | 0.85 | TACR1 (0.50) | ESR1ESR2FOLH1TSHRMIF | |
| SCHEMBL3048691 | 0.85 | TACR1 (0.50) | ESR1ESR2FOLH1TSHRMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028350-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |