Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.72 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 4/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | ADA | P00813 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1130016 | 0.84 | ADRB2 (1.00) | ADRB2HTR1DHTR2AHTR6MTNR1A | |
| Hydrochloric Acid SCHEMBL7680700 | 0.83 | ADRB2 (0.97) | ADRB2HTR1DHTR2AHTR6MTNR1A | |
| SCHEMBL12720754 | 0.80 | ADRB2 (0.71) | ADRB2HTR1DHTR2AHTR6MTNR1A | |
| SCHEMBL3320875 | 0.77 | HTR1D (0.68) | ADRB2HTR1DHTR2AHTR6MTNR1A | |
| SCHEMBL14297213 | 0.76 | HTR1D (0.66) | ADRB2HTR1DHTR2AHTR6MTNR1A | |
| SCHEMBL379053 | 0.75 | ADRB2 (0.64) | ADRB2HTR1DHTR2AHTR6KDM4E | |
| SCHEMBL5923660 | 0.75 | ADRB2 (0.64) | ADRB2HTR1DHTR2AHTR6KDM4E | |
| Hydrochloric Acid SCHEMBL7807646 | 0.75 | HTR1D (0.64) | ADRB2HTR1DHTR2AHTR6MTNR1A | |
| SCHEMBL21333400 | 0.75 | HTR1D (0.64) | ADRB2HTR1DHTR2AHTR6MTNR1A | |
| SCHEMBL658829 | 0.75 | HTR1D (0.64) | ADRB2HTR1DHTR2AHTR6MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028350-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |