Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | BLM | P54132 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.53 |
| ▸ | APEX1 | P27695 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31392613 | 0.84 | RAD52 (0.60) | TDP1MAPTKDM4EADRB2ADRB1 | |
| SCHEMBL521779 | 0.84 | MAPT (0.58) | TDP1MAPTKDM4EADRB2ADRB1 | |
| SCHEMBL521780 | 0.84 | MAPT (0.58) | TDP1MAPTKDM4EADRB2ADRB1 | |
| SCHEMBL25100812 | 0.83 | TSHR (0.63) | BLMCYP3A4TSHRCYP1A2PMP22 | |
| SCHEMBL17053665 | 0.82 | MAPT (0.56) | TDP1MAPTKDM4EADRB2ADRB1 | |
| SCHEMBL7542267 | 0.80 | KDM4E (0.56) | TDP1MAPTKDM4EADRB2ADRB1 | |
| SCHEMBL28126607 | 0.80 | KDM4E (0.56) | TDP1MAPTKDM4EADRB2ADRB1 | |
| SCHEMBL31419995 | 0.80 | KDM4E (0.56) | TDP1MAPTKDM4EADRB2ADRB1 | |
| SCHEMBL22971597 | 0.79 | MAPT (0.54) | TDP1MAPTKDM4EADRB2ADRB1 | |
| SCHEMBL9722026 | 0.78 | HIF1A (0.55) | KDM4EADRB2ADRB1BLMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028350-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |