Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | APEX1 | P27695 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31419995 | 1.00 | KDM4E (0.56) | KDM4EKMT2AMEN1SMN1; SMN2CNR2 | |
| SCHEMBL7542267 | 1.00 | KDM4E (0.56) | KDM4EKMT2AMEN1SMN1; SMN2CNR2 | |
| SCHEMBL28339091 | 0.82 | KDM4E (0.70) | KDM4EKMT2AMEN1SMN1; SMN2CNR2 | |
| SCHEMBL13993320 | 0.82 | KDM4E (0.70) | KDM4EKMT2AMEN1SMN1; SMN2CNR2 | |
| SCHEMBL14274010 | 0.82 | KDM4E (0.70) | KDM4EKMT2AMEN1SMN1; SMN2CNR2 | |
| SCHEMBL7099619 | 0.82 | KDM4E (0.56) | KDM4EKMT2AMEN1SMN1; SMN2CNR2 | |
| SCHEMBL28993748 | 0.82 | KDM4E (0.56) | KDM4EKMT2AMEN1SMN1; SMN2CNR2 | |
| Hydrochloric Acid SCHEMBL7106622 | 0.81 | KDM4E (0.54) | KDM4EKMT2AMEN1SMN1; SMN2CNR2 | |
| SCHEMBL28341672 | 0.80 | MEN1 (0.63) | KDM4EKMT2AMEN1SMN1; SMN2CNR2 | |
| SCHEMBL25100809 | 0.80 | TDP1 (0.53) | KDM4EKMT2AMEN1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397229-A | Method for preparing (R)-4-(2-(benzyl (methyl) amino)-hydroxyethyl)benzene-1,2-diol | 蚌埠丰原医药科技发展有限公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-106397229-A | Method for preparing (R)-4-(2-(benzyl (methyl) amino)-hydroxyethyl)benzene-1,2-diol | 蚌埠丰原医药科技发展有限公司 | 2017-02-15 | — | — | CN | disclosed |