Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320573 | 1.00 | TAAR1 (0.54) | TAAR1HIF1AHTR3ATSHRNFKB1 | |
| SCHEMBL6320570 | 0.83 | TAAR1 (0.50) | TAAR1HIF1AHTR3ATSHRNFKB1 | |
| SCHEMBL16327150 | 0.83 | AOC3 (0.48) | TAAR1ALDH1A1SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL1205131 | 0.81 | AOC3 (0.72) | TAAR1KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6281264 | 0.81 | AOC3 (0.72) | ALDH1A1SMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1239178 | 0.81 | AOC3 (0.47) | TAAR1HIF1ANFKB1HTR1ATHPO | |
| SCHEMBL529255 | 0.81 | AOC3 (0.52) | TAAR1HIF1AHTR3ATSHRNFKB1 | |
| SCHEMBL12238827 | 0.80 | TAAR1 (0.47) | TAAR1HIF1AHTR3ATSHRNFKB1 | |
| SCHEMBL29633156 | 0.80 | TAAR1 (0.47) | TAAR1HIF1AHTR3ATSHRNFKB1 | |
| SCHEMBL804251 | 0.80 | AOC3 (0.70) | TAAR1TDP1KDM4ESMN1; SMN2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023028350-A1 | THERAPEUTIC COMPOSITIONS AND RELATED METHODS | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |