⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26793451 | 0.82 | — | — | |
| SCHEMBL29307161 | 0.80 | HSD17B10 (0.50) | — | |
| SCHEMBL24554745 | 0.79 | — | — | |
| SCHEMBL6934510 | 0.77 | — | — | |
| SCHEMBL15087919 | 0.76 | LMNA (0.30) | — | |
| SCHEMBL1911283 | 0.76 | LMNA (0.30) | — | |
| SCHEMBL7156185 | 0.74 | — | — | |
| SCHEMBL28896794 | 0.73 | TSHR (0.39) | — | |
| SCHEMBL13002239 | 0.72 | — | — | |
| SCHEMBL19275786 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023025276-A1 | POTASSIUM CHANNEL MODULATOR, COMPOSITION AND APPLICATION | 杭州和正医药有限公司 | 2023-03-02 | — | — | WO | disclosed |