Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 8/20 | 0.64 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25774695 | 0.86 | KCNQ2 (0.56) | KCNQ2MAOBSCN9AJAK2JAK1 | |
| SCHEMBL25775366 | 0.85 | KCNQ2 (0.52) | KCNQ2MAOBSCN9AMAPTNR3C2 | |
| SCHEMBL25774116 | 0.85 | KCNQ2 (0.62) | KCNQ2MAOBSCN9AMAPTNR3C2 | |
| SCHEMBL30487393 | 0.85 | KCNQ2 (0.74) | KCNQ2MAOBSCN9A | |
| SCHEMBL25774244 | 0.84 | KCNQ2 (0.47) | KCNQ2MAOBMAPTGRIN2DGRIN3B | |
| SCHEMBL31020108 | 0.84 | KCNQ2 (0.73) | KCNQ2MAOBGRIN2DGRIN3BGRIN1 | |
| SCHEMBL25293900 | 0.83 | KCNQ2 (0.57) | KCNQ2MAOBSCN9AMAPTNR3C2 | |
| SCHEMBL25246726 | 0.83 | KCNQ2 (0.57) | KCNQ2MAOBMAPTNR3C2RAB9A | |
| SCHEMBL25774569 | 0.83 | GRIN2D (0.50) | KCNQ2MAOBMAPTGRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL31546558 | 0.82 | KCNQ2 (0.56) | KCNQ2MAOBMAPTNR3C2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023025276-A1 | POTASSIUM CHANNEL MODULATOR, COMPOSITION AND APPLICATION | 杭州和正医药有限公司 | 2023-03-02 | — | — | WO | disclosed |