Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 9/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31020115 | 0.87 | KCNQ2 (0.47) | KCNQ2MAOBMAPTNR3C2 | |
| SCHEMBL25290650 | 0.87 | KCNQ2 (0.47) | KCNQ2MAOBMAPTNR3C2 | |
| SCHEMBL25101483 | 0.85 | KCNQ2 (0.64) | KCNQ2MAOBSCN9AJAK2JAK1 | |
| SCHEMBL30487340 | 0.84 | KCNQ2 (0.45) | KCNQ2MAOBMAPTNR3C2 | |
| SCHEMBL25774695 | 0.84 | KCNQ2 (0.56) | KCNQ2MAOBSCN9AADAMTS4JAK2 | |
| SCHEMBL25246751 | 0.83 | KCNQ2 (0.78) | KCNQ2 | |
| SCHEMBL30487371 | 0.83 | KCNQ2 (0.78) | KCNQ2 | |
| SCHEMBL25250592 | 0.81 | KCNQ2 (0.46) | KCNQ2MAOBMAPTNR3C2 | |
| SCHEMBL30487385 | 0.81 | KCNQ2 (0.46) | KCNQ2MAOBMAPTNR3C2 | |
| SCHEMBL25246726 | 0.76 | KCNQ2 (0.57) | KCNQ2MAOBMAPTNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125935-A1 | BENZOPYRIDINE DERIVATIVE REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |