SCHEMBL25102

SCHEMBL25102

CC1CCOC2(CCCC2)C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18899114 1.00 ATM (0.30) ATML3MBTL1
SCHEMBL24541 0.98
SCHEMBL18372673 0.95 ATM (0.30) ATML3MBTL1
SCHEMBL26050137 0.95 ATM (0.30) ATML3MBTL1
SCHEMBL26052834 0.95 ATM (0.30) ATML3MBTL1
SCHEMBL24571795 0.91
SCHEMBL21185111 0.91
SCHEMBL18576891 0.87 CYP1A2 (0.35) ATML3MBTL1
SCHEMBL18576605 0.87 CYP1A2 (0.35) ATML3MBTL1
SCHEMBL18573248 0.87 CYP1A2 (0.35) ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023192375-A1 HSD17B13 INHIBITORS AND USES THEREOF FL2022-001, INC. (US) 2023-10-05 WO disclosed
EP-4122927-A1 SUBSTITUTED PYRIMIDINE OR PYRIDINE AMINE DERIVATIVE, COMPOSITION THEREOF, AND MEDICAL USE THEREOF Shanghai Haiyan Pharmaceutical Technology Co., Ltd. (CN) 2023-01-25 EP disclosed
WO-2021043209-A1 RET INHIBITOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF 广东东阳光药业有限公司 2021-03-11 WO disclosed
WO-2020147848-A1 TRICYCLIC SUBSTITUTED OXASPIRO DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF 上海海雁医药科技有限公司 2020-07-23 WO disclosed
US-9845443-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2017-12-19 US disclosed
US-9845443-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2017-12-19 US disclosed
US-9845443-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2017-12-19 US disclosed
US-20170355695-A1 SMYD Inhibitors Epizyme, Inc. (US) 2017-12-14 US disclosed
US-20170190676-A1 Isoxazole Carboxamide Compounds Epizyme, Inc. (US) 2017-07-06 US disclosed
EP-2609184-B1 PERFUMERY COMPOSITIONS AND SYNTHESIS OF A ODORANT VAZE KEDAR RAMESH (IN) 2017-02-15 EP disclosed
US-20160024424-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2016-01-28 US disclosed
US-20160024424-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2016-01-28 US disclosed
US-9187709-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2015-11-17 US disclosed
US-9187709-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2015-11-17 US disclosed
US-9187709-B2 Synthesis of a novel odorant VAZE KEDAR RAMESH (IN) 2015-11-17 US disclosed
EP-2609184-A1 SYNTHESIS OF A NOVEL ODORANT Vaze, Kedar Ramesh (IN) 2013-07-03 EP disclosed
US-20130157923-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2013-06-20 US disclosed
US-20130157923-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2013-06-20 US disclosed
US-20130157923-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2013-06-20 US disclosed
WO-2012025934-A1 SYNTHESIS OF A NOVEL ODORANT VAZE KEDAR RAMESH (IN) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170190676-A1 Isoxazole Carboxamide Compounds SMYD3, SMYD2, SNRPD3 ATM 1643/4885L3MBTL1 1205/4885
US-20170355695-A1 SMYD Inhibitors SMYD3, SMYD2, SMURF2 ATM 2613/4885L3MBTL1 660/4885
US-20160024424-A1 SYNTHESIS OF A NOVEL ODORANT OR10J3, OR51E2, TAS2R10 ATM 3024/4885L3MBTL1 421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.