TAS2R10

Taste receptor type 2 member 10 · Q9NYW0 · TAS2R10 on Sugi Atlas →

1,467 patent compounds predicted against TAS2R10, 924 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Strychnine (SCHEMBL93798)	1.00	2/20
Brucine (SCHEMBL113229)	1.00	2/20
Brucine (SCHEMBL1648976)	1.00	2/20
Brucine (SCHEMBL10307298)	1.00	2/20
Brucine (SCHEMBL12293782)	1.00	2/20
Strychnine (SCHEMBL12549549)	1.00	2/20
SCHEMBL12667208	1.00	2/20
Brucine (SCHEMBL14029321)	1.00	2/20
Strychnine (SCHEMBL14029424)	1.00	2/20
Strychnine (SCHEMBL14047653)	1.00	2/20
Strychnine (SCHEMBL14117483)	1.00	2/20
Brucine (SCHEMBL524833)	0.98	2/20
Brucine (SCHEMBL6233075)	0.98	2/20
Brucine (SCHEMBL6794678)	0.98	2/20
Brucine (SCHEMBL7253414)	0.98	2/20
Brucine (SCHEMBL7427549)	0.98	2/20
Strychnine (SCHEMBL184168)	0.98	2/20
Strychnine (SCHEMBL5317062)	0.98	2/20
Strychnine (SCHEMBL15475787)	0.95	2/20
Brucine (SCHEMBL577757)	0.94	2/20

Clinical trials — most relevant to TAS2R10 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Clinical Trial of Efficacy and Safety of Raphamin in the Treatment of Coronavirus Disease 2019 in Outpatients	PHASE3	COMPLETED
Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes	PHASE2	COMPLETED
Role of the Gut Sweet Taste Receptor in the Secretion of Glucagon-like Peptide-1 and Peptide YY	PHASE1	COMPLETED
Role of the Gut Sweet Taste Receptor in the Secretion of Satiation Peptides	PHASE1	COMPLETED
Sweet Taste Receptors and the Secretion of Glucagon-like Peptide-1 and Peptide YY	PHASE1	COMPLETED
TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries	nan	COMPLETED
Vegetables Intake and Polymorphism TAS2R38 Gene by Healthy Adults	nan	COMPLETED
Fructose and Glucose and TAS1R2 in Type 1 Diabetes	nan	COMPLETED
Flavour Programming: Fruit and Vegetable Palatability	nan	COMPLETED
NUTRACORE, Glycaemic Index and Appetite	nan	COMPLETED
Sensory Study: Taste and Tongue Biology	nan	COMPLETED
Allele-specific Expression of a Bitter Taste Receptor	nan	COMPLETED
The Effect of Lactisole on the Responses to Glucose Solution	nan	UNKNOWN
Study of Taste Deficits	nan	COMPLETED
Genetic Variability in Taste Perception	nan	COMPLETED
Ibuprofen Inhibits Human Sweet Taste	nan	COMPLETED
Bitter Taste Receptors in Oropharynx Cancer	nan	UNKNOWN
Sucralose and Lactisole Additions to OGTT in Humans	nan	COMPLETED
CD36 and Human Fat Taste Perception	nan	COMPLETED
A Study of the Function of Hormones Present In Taste Buds	nan	COMPLETED
Factors Affecting Salt Intake in Young Adults	nan	UNKNOWN
Astringency and Oral Health	nan	COMPLETED
The Effect of Artificial Sweeteners on Blood Glucose Response	nan	WITHDRAWN
Impacts of Sugar-Sweetened Beverage on Body Weight	nan	COMPLETED
Taste Preferences for Nutritive and Non Nutritive Sweeteners Among Children and Adults	nan	COMPLETED
The Obese Taste Bud Study	nan	UNKNOWN
Sensitive Periods in Early Flavor Learning	nan	COMPLETED
The Molecular Basis for a Broad Range of Phenotypes Related to hTAS2R38	nan	COMPLETED
Gustin Gene Polymorphism and 6-n-propylthiouracil (PROP) Taste	nan	COMPLETED
Adaptation Strategies for Coping With the Impact of Sensory Alterations on Eating Behavior in Children With Cancer: A Qualitative Study From the Perspective of Children and Parents	nan	NOT_YET_RECRUITING

Related proteins — ESM-2 sequence neighbours (a TAS2R10 binder may also engage these)

Protein	Name	Similarity
Q645V0	—	1.000	Q645V0 →
Q646D7	—	1.000	Q646D7 →
Q645Z4	—	1.000	Q645Z4 →
Q646F5	—	0.999	Q646F5 →
Q646B5	—	0.998	Q646B5 →
Q7M722	—	0.997	Q7M722 →
Q9JKT5	—	0.995	Q9JKT5 →
Q645T0	—	0.994	Q645T0 →
Q645U8	—	0.994	Q645U8 →
Q646G5	—	0.994	Q646G5 →
Q7M713	—	0.993	Q7M713 →
Q67ET3	—	0.993	Q67ET3 →
Q7M711	—	0.993	Q7M711 →
TAS2R8	Taste receptor type 2 member 8	0.993	landscape →
Q7M723	—	0.993	Q7M723 →
Q646C6	—	0.993	Q646C6 →
Q9JKT8	—	0.992	Q9JKT8 →
Q5Y4Z2	—	0.992	Q5Y4Z2 →
Q67ES6	—	0.992	Q67ES6 →
Q9JKE9	—	0.992	Q9JKE9 →
Q646B6	—	0.991	Q646B6 →
Q7M720	—	0.991	Q7M720 →
TAS2R13	Taste receptor type 2 member 13	0.991	landscape →
TAS2R9	Taste receptor type 2 member 9	0.991	landscape →
Q7TQA8	—	0.991	Q7TQA8 →
Q646A3	—	0.990	Q646A3 →
Q7M721	—	0.990	Q7M721 →
Q7M725	—	0.990	Q7M725 →
Q9JKT4	—	0.990	Q9JKT4 →
Q645U9	—	0.990	Q645U9 →