Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25105273 | 0.86 | KDM4E (0.41) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL25103101 | 0.85 | NPC1 (0.42) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL25104712 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL30158309 | 0.82 | KMT2A (0.36) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL25103104 | 0.82 | KDM4E (0.40) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL25104556 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL25102855 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1MEN1KMT2AGAA | |
| SCHEMBL25103276 | 0.77 | KDM4E (0.42) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25104074 | 0.76 | PDE4D (0.40) | KDM4EALDH1A1MEN1KMT2ANR4A2 | |
| SCHEMBL543331 | 0.76 | ALDH1A1 (0.46) | KDM4EALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4395892-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023034812-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| EP-4110459-A1 | HETEROCYCLIC AMIDES AND THEIR USE FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2023-01-04 | — | — | EP | disclosed |