SCHEMBL2510604

SCHEMBL2510604

Nc1[nH]cnc1C(=O)NC1O[C@H](CO)[C@@H](O)[C@H]1OP(=O)(O)O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.44
CA1 P00915 4/20 0.37
CA2 P00918 4/20 0.37
CA9 Q16790 4/20 0.37
FGF1 P05230 1/20 0.37
FGF2 P09038 1/20 0.37
VEGFA P15692 1/20 0.37
HPSE Q9Y251 1/20 0.37
AKR1B1 P15121 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8329378 1.00 ADORA1 (0.44) ADORA1CA1CA2CA9FGF1
SCHEMBL3812504 0.88 PYGB (0.40) CA1CA2CA9FGF1FGF2
SCHEMBL3812993 0.86 CA1 (0.38) CA1CA2CA9FGF1FGF2
SCHEMBL18642492 0.85 CA1 (0.50) CA1CA2CA9AKR1B1
SCHEMBL6934741 0.85 CA1 (0.50) CA1CA2CA9AKR1B1
SCHEMBL3810831 0.85 CA1 (0.50) CA1CA2CA9AKR1B1
SCHEMBL7253811 0.85 CA1 (0.50) CA1CA2CA9AKR1B1
SCHEMBL9616492 0.85 CA1 (0.50) CA1CA2CA9AKR1B1
SCHEMBL2508682 0.85 ADORA1 (0.37) ADORA1FGF1FGF2VEGFAHPSE
SCHEMBL3816892 0.83 MAPK1 (0.39) CA1CA2CA9AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140309186-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION 2014-10-16 US disclosed
US-20110246081-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION (US) 2011-10-06 US disclosed