Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 11/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ILK | Q13418 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410338 | 0.91 | HRH4 (0.39) | HRH4CYP1A2CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL2414980 | 0.81 | HRH4 (0.40) | HRH4CYP1A2CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL2410925 | 0.80 | ALDH1A1 (0.43) | HRH4CYP1A2CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL2413748 | 0.79 | HRH4 (0.43) | HRH4 | |
| SCHEMBL2416112 | 0.78 | CYP1A2 (0.34) | HRH4CYP1A2CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL2411118 | 0.77 | MCHR1 (0.41) | HRH4 | |
| SCHEMBL2411482 | 0.77 | HRH4 (0.39) | HRH4ALOX15KDM4EMAPK1 | |
| SCHEMBL2415416 | 0.75 | HRH4 (0.37) | HRH4CYP1A2CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL2413123 | 0.75 | ADORA2A (0.44) | HRH4 | |
| SCHEMBL2412210 | 0.75 | CXCR4 (0.38) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312606-B1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | OREAL (FR) | 2011-09-21 | — | — | EP | claimed |