Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.58 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6386485 | 0.78 | — | — | |
| SCHEMBL3464079 | 0.77 | FAAH (0.37) | BRD4FAAH | |
| SCHEMBL5709310 | 0.75 | — | — | |
| SCHEMBL21964862 | 0.75 | — | — | |
| SCHEMBL18821186 | 0.75 | — | — | |
| SCHEMBL23952371 | 0.74 | — | — | |
| SCHEMBL15850804 | 0.74 | — | — | |
| SCHEMBL1929098 | 0.74 | — | — | |
| SCHEMBL19357292 | 0.74 | — | — | |
| SCHEMBL19331460 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373617-A1 | MIXTURES OF ITACONIC ACID OR ITACONIC ACID DERIVATIVES AND PRIMARY AMINES FOR PRODUCING 1,3- AND 1,4-ALKYL METHYL PYRROLIDONES | BASF SE (DE) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010063617-A1 | MIXTURES OF ITACONIC ACID OR ITACONIC ACID DERIVATIVES AND PRIMARY AMINES FOR PRODUCING 1,3- AND 1,4-ALKYL METHYL PYRROLIDONES | BASF SE (DE) | 2010-06-10 | — | — | WO | disclosed |