Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25839621 | 0.86 | KDM4E (0.38) | KDM4EHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL25118166 | 0.78 | HSD17B10 (0.38) | KDM4EHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL25117825 | 0.78 | ALDH1A1 (0.52) | KDM4EHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL25117806 | 0.76 | KDM4E (0.40) | KDM4EHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL25839421 | 0.75 | KDM4E (0.39) | KDM4EHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL25839761 | 0.75 | ALDH1A1 (0.35) | KDM4EHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL25118110 | 0.75 | ALDH1A1 (0.35) | KDM4EHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL25841360 | 0.73 | KDM4E (0.38) | KDM4EHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL25118111 | 0.73 | ALDH1A1 (0.34) | KDM4EHPGDHSD17B10TSHRCASP1 | |
| SCHEMBL25118012 | 0.73 | PDE4B (0.40) | KDM4EHPGDHSD17B10TSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4163283-A1 | COMPOUND HAVING MACROCYCLIC STRUCTURE AND USE THEREOF | Scinnohub Pharmaceutical Co., Ltd (CN) | 2023-04-12 | — | — | EP | disclosed |